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Current Students> Undergraduate> Course Homepages> Upper Year Session 1

MATH5906 Design and Analysis of Clinical Trials

MATH5906 is a Mathematics Level V course. See the course overview below.

Units of credit: 6

Prerequisites:

Cycle of offering: not offered every year.

Graduate attributes: the course will enhance your research, inquiry and analytical thinking abilities.

More information: this recent course handout (pdf) contains information about course objectives, assessment, course materials and the syllabus. (This pdf will usually be updated by the end of the first week of the semester.)

The Online Handbook entry contains up-to-date timetabling information.

If you are currently enrolled in MATH5906, you can log into the My eLearning Vista instance of this course.

Course Overview

This course will provide an introduction to statistical methodology used in the conduct of randomized controlled clinical trials.
Topics include: an introduction to the basic philosophy and history of the randomized controlled trial, design issues such as methods of randomization and sample size determination, interim analyses and group sequential trials, methods for longitudinal clinical trials, crossover trials, meta-analysis, and surrogate outcomes.
Extensive use will be made of the computer language R in analysing real datasets.


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